MSDS OF ALPHA CYCLODEXTRIN

The Material Safety Data Sheet (MSDS/SDS) for Alpha Cyclodextrin is a vital resource for safe chemical management. This cyclic starch derivative, used in pharmaceuticals, food, and cosmetics, requires clear safety guidelines due to its interaction with hydrophobic compounds.

The SDS outlines physical/chemical traits (e.g., solubility, stability), hazards (e.g., mild irritation risks), and emergency steps (e.g., eye rinsing, ventilation). It ensures workplace safety by mandating PPE, proper storage (dry, cool conditions), and incompatibility warnings (e.g., strong oxidizers).

Additionally, it addresses regulatory compliance—guiding disposal per environmental rules and transport labeling under global standards (e.g., OSHA, REACH). By consolidating safety, handling, and legal data, the SDS minimizes risks, protects users, and ensures accountability.

  • Seller: Miss He
  • Mobile Phone: 15239123436
  • E-mail: 875287035@qq.com
  • Address: No. 44, Longshou 1st Street, Huichang Street, Mengzhou, Jiaozuo City, Henan Province, China

Chemical Safety Data Sheet MSDS / SDS

α-Cyclodextrin

Revision Date:2025-02-01 Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier
  • Product name: α-Cyclodextrin
  • CBnumber: CB0163457
  • CAS: 10016-20-3
  • EINECS Number: 233-007-4
  • Synonyms: α-cyclodextrin,Alpha-Cyclodextrin
Relevant identified uses of the substance or mixture and uses advised against
  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none
Company Identification
  • Company: Jiaozuo Jiaji Biotechnology Co., Ltd.
  • Address: No. 44, Longshou 1st Street, Huichang Street, Mengzhou, Jiaozuo City, Henan Province, China
  • Telephone: +086 152 3912 3436

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements
  • Signal word: No signal word
  • Hazard statement(s): none
  • Prevention: none
  • Response: none
  • Storage: none
  • Disposal: none

SECTION 3: Composition/information on ingredients

Substance
  • Product name: α-Cyclodextrin
  • Synonyms: α-cyclodextrin,Alpha-Cyclodextrin
  • CAS: 10016-20-3
  • EC number: 233-007-4
  • MF: C36 H60 O30
  • MW: 972.84

SECTION 4: First aid measures

Description of first aid measures
General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides Combustible.
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
No data available

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Avoid breathing dust. For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Store in cool place.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter
Hazard composition and occupational exposure limits Does not contain substances with occupational exposure limits.
Exposure controls
Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties
  • Appearance solid
  • OdourNo data available
  • Odour ThresholdNo data available
  • pH5.0-8.0 (1% in solution)
  • Melting point/freezing pointMelting point/range: >278 °C
  • Initial boiling point and boiling range784.04°C (rough estimate)
  • Flash pointNo data available
  • Evaporation rateNo data available
  • Flammability (solid, gas)No data available
  • Upper/lower flammability or explosive limitsNo data available
  • Vapour pressureNo data available
  • Vapour densityNo data available
  • Relative densityNo data available
  • Water solubilityH2O: 50 mg/mL
  • Partition coefficient: n-octanol/waterNo data available
  • Autoignition temperatureNo data available
  • Decomposition temperatureNo data available
  • ViscosityNo data available
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available
Other safety information
No data available

SECTION 10: Stability and reactivity

Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
No data available
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects
Acute toxicity LD50 Oral - Rat - > 10.000 mg/kg Remarks: (External MSDS) Skin corrosion/irritation Skin - Rabbit Result: No skin irritation Remarks: (External MSDS) Serious eye damage/eye irritation Eyes - Rabbit Result: Eye irritation Remarks: (External MSDS) Respiratory or skin sensitisation Remarks: (External MSDS) Germ cell mutagenicity No data available Mutagenicity (mammal cell test): micronucleus. Result: negative (External MSDS) Ames test Salmonella typhimurium Result: negative (External MSDS) Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity No data available Specific target organ toxicity - single exposure No data available Specific target organ toxicity - repeated exposure No data available Aspiration hazard No data available Additional Information RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

SECTION 12: Ecological information

Toxicity
No data available
Persistence and degradability
No data available
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available

SECTION 13: Disposal considerations

Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
Contaminated packaging
Dispose of as unused product.

SECTION 14: Transport information

UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods IMDG: Not dangerous goods
14.3 IATA: Not dangerous goods Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous Chemicals China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/ Measures for Environmental Management of New Chemical Substances European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/ Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/ Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/ Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/ EC Inventory:Listed. Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/ New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/

SECTION 16: Other information

Abbreviations and acronyms
  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple 【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp 【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/ 【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en 【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg 【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp 【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm 【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/ 【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home 【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/ Disclaimer: The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS. Recommended Products α-Cyclodextrin SDS HEXAKIS(2,3,6-TRI-O-METHYL)-ALPHA-CYCLODEXTRIN SDS ALPHA-CYCLODEXTRIN HYDRATE SDS -CYCLODEXTRIN PHOSPHATE SODIUM SA SDS α-Lipoic Acid SDS 2-Hydroxypropyl-β-cyclodextrin SDS HEXAKIS-6-(DIMETHYL-TERT-BUTYLSILYL)-ALPHA-CYCLODEXTRIN SDS β-Cyclodextrin SDS gamma-Cyclodextrin SDS Diethylstilbestrol SDS